HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1469946Generated: October 31, 2026
2-Amino-4,5-dimethyl-1,3-thiazole → HCID 66860587, compound
https://huagongshe.com/reaction/1469946
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | 4-(Bromomethyl)oxane | HCID 2773286 | — |
| Product | HCID 66860587 | HCID 66860587 | 13% |
Reaction Steps
A mixture of 4,5-dimethyl-thiazol-2-ylamine (0.36 g, 2.8 mmol) and 4-bromomethyltetrahydropyran (0.75 g, 4.2 mmol) was heated at 85° C. for 16 hours. The residue purified by preparative HPLC to afford 80 mg (13%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09006275B2 |
|---|
| Source dataset | uspto-grants-2015_04 |
|---|
| ORD ID | ord-ed65b32d540e4f08aed835cae5a7d91a |
|---|
| Source note | uspto-grants-2015_04 |
|---|
