HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Adamantanecarboxylic acid → HCID 178435114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Adamantanecarboxylic acid | HCID 13235 | — |
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | (Bromomethyl)cyclobutane | HCID 2734658 | — |
| Product | HCID 178435114 | HCID 178435114 | — |
Reaction Steps
4,5-Dimethylthiazol-2-ylamine, bromomethylcyclobutane and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.60-1.75 (m, 6H) 1.75-1.93 (m, 10H) 1.92-2.06 (m, 5H) 2.15 (s, 3H) 2.18 (s, 3H) 2.64-2.74 (m, 1H) 4.22 (d, J=7.18 Hz, 2H); MS (ESI) m/z 359 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006275B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-e8ec96521a1a48f78bbb0a1cedcebbfe |
| Source note | uspto-grants-2015_04 |