HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Adamantanecarboxylic acid → HCID 178435115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Adamantanecarboxylic acid | HCID 13235 | — |
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | 1-(Bromomethyl)-4-(1,1-dimethylethyl)benzene | HCID 87836 | — |
| Product | HCID 178435115 | HCID 178435115 | — |
Reaction Steps
4,5-Dimethylthiazol-2-ylamine, 1-bromomethyl-4-tert-butylbenzene and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.24 (s, 9H) 1.54-1.73 (m, 6H) 1.82 (d, J=2.50 Hz, 6H) 1.92-2.01 (m, 3H) 2.10 (s, 3H) 2.13 (s, 3H) 5.39 (s, 2H) 7.19 (d, J=8.42 Hz, 2H) 7.36 (d, J=8.42 Hz, 2H); MS (ESI) m/z 437 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006275B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-5d0be2b12997456b9d49d8a306ecef1f |
| Source note | uspto-grants-2015_04 |