HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Adamantanecarboxylic acid → HCID 178435116, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Adamantanecarboxylic acid | HCID 13235 | — |
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | 3-(Bromomethyl)pyridine | HCID 245934 | — |
| Product | HCID 178435116 | HCID 178435116 | — |
Reaction Steps
4,5-Dimethylthiazol-2-ylamine, 3-bromomethylpyridine and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.49-1.71 (m, 6H) 1.74 (d, J=2.50 Hz, 6H) 1.85-2.02 (m, 3H) 2.19 (d, J=11.54 Hz, 6H) 5.44 (s, 2H) 7.29 (t, J=7.33 Hz, 2H) 7.69-7.85 (m, 1H) 8.49 (d, J=4.68 Hz, 1H); MS (ESI) m/z 382 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006275B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-6efc0ac354a44d1081181c94e8ba8f2d |
| Source note | uspto-grants-2015_04 |