3-Bromo-1-propanol → HCID 66858520, compound

HRID 1469995Notes

Reaction equation

HRID 1469995 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH2:8])[S:5][C:6]=1[CH3:7].[Br:9][CH2:10][CH2:11][CH2:12][OH:13]>>[BrH:9].[NH:8]=[C:4]1[N:3]([CH2:10][CH2:11][CH2:12][OH:13])[C:2]([CH3:1])=[C:6]([CH3:7])[S:5]1

Participants

3

Reactant 2

HCID 123083-Bromo-1-propanolHCID 732382-Amino-4,5-dimethyl-1,3-thiazole

Product 1

HCID 66858520HCID 66858520, compound

Procedure

4,5-dimethyl-thiazol-2-ylamine (2.0 g, 16 mmol) and 3-bromo-propan-1-ol (1.6 mL, 19 mmol) were processed according to the method of Example 46A to afford the title compound.

Sources & evidence

ORD record
ord-eb99fedca0cd46518706d6c46b942c16
Source dataset
uspto-grants-2015_04
Patent number
US09006275B2

Reaction notes

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