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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1470038Generated: October 26, 2026

Hexafluoroacetone trihydrate → 2-(2-Amino-4-methylthiazol-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol

https://huagongshe.com/reaction/1470038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexafluoroacetone trihydrateHCID 36719—
Reactant2-Amino-4-methylthiazoleHCID 74143—
Product2-(2-Amino-4-methylthiazol-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-olHCID 11357953—

Reaction Steps

The title compound was prepared from commercially available of 4-methylthiazol-2-amine (Aldrich) and hexafluoroacetone trihydrate (Aldrich) according to the procedure described in European Journal of Organic Chemistry, (21), 4286-4291; 2003. MS (ESI+) m/z 281 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09006275B2
Source datasetuspto-grants-2015_04
ORD IDord-1aef0b302db24012815f1c988946a791
Source noteuspto-grants-2015_04