反应详情

Benzyl 4-hydroxy-2-(pyridin-2-yl)pyrimidin-5-ylcarbamate (10-d) (1 g, 3.1 mmol) in methanol (20 ml) was hydrogenated under 1 atm of hydrogen in the presence of Pd/C (500 mg) overnight. The mixture was filtered and the filtrate was concentrated to provide the crude product, 10-e (240 mg).

1. filtrationThe mixture was filtered
2. concentrationthe filtrate was concentrated