1-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid → HCID 66779257, compound

Participants

Reaction Steps

The title compound was prepared by procedure G using 1-(4-fluoro-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (26.21 mg; 0.11 mmol; 1.20 eq.) instead of 1-(2-hydroxy-2-methyl-propyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid and using 3-fluoro-4-[(2-phenylfuro[3,2-b]pyridin-7-yl)oxy]aniline (30.00 mg; 0.09 mmol; 1.00 eq.) instead of 4-[(2-phenylfuro[3,2-b]pyridin-7-yl)oxy]aniline, and was obtained as a beige solid (36 mg, 72%). (HPLC (method F): 89%, RT: 4.63 min); MS (m/z) 536 [M+H]+, RT: 4.2 min.

Provenance & Evidence