HRID1470393

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID74372

Benzoyl chloride, 4-(1,1-dimethylethyl)-

C11H13ClO

反应SMILES：Cc1c(N)cccc1-c1ccnc2cc(-c3ccc(C(=O)N4CCCC4)cc3)oc12

HCID86694440

未命名化合物

PRODUCTS

产物

反应SMILES：Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1ccnc2cc(-c3ccc(C(=O)N4CCCC4)cc3)oc12

HCID56848932

未命名化合物

PROCEDURE

实验过程

The compound was synthesized according to the procedure M using 2-methyl-3-{2-[4-(pyrrolidin-1-ylcarbonyl)phenyl]furo[3,2-b]pyridin-7-yl}aniline (50 mg, 0.13 mmol) and 4-tert-butylbenzoyl chloride (27.21 mg, 0.14 mmol). The title compound was obtained as white solid (6.00 mg, 9%). HPLC (method F): 100%, RT=4.714 min. MS: m/z=558 [M+H]+, RT=4.85 min.

WORKUP

后处理

customThe compound was synthesized

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-b6759fd1f10b427e9958d2b535b0e935
来源数据集: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US09006440B2
来源说明: uspto-grants-2015_04

反应SMILES

[CH3:1][C:2]1[C:8]([C:9]2[CH:14]=[CH:13][N:12]=[C:11]3[CH:15]=[C:16]([C:18]4[CH:23]=[CH:22][C:21]([C:24]([N:26]5[CH2:30][CH2:29][CH2:28][CH2:27]5)=[O:25])=[CH:20][CH:19]=4)[O:17][C:10]=23)=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[C:31]([C:35]1[CH:43]=[CH:42][C:38]([C:39](Cl)=[O:40])=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]>>[C:31]([C:35]1[CH:36]=[CH:37][C:38]([C:39]([NH:4][C:3]2[CH:5]=[CH:6][CH:7]=[C:8]([C:9]3[CH:14]=[CH:13][N:12]=[C:11]4[CH:15]=[C:16]([C:18]5[CH:23]=[CH:22][C:21]([C:24]([N:26]6[CH2:30][CH2:29][CH2:28][CH2:27]6)=[O:25])=[CH:20][CH:19]=5)[O:17][C:10]=34)[C:2]=2[CH3:1])=[O:40])=[CH:42][CH:43]=1)([CH3:34])([CH3:32])[CH3:33]