Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1470475Generated: October 31, 2026

2-Oxa-7-azaspiro[3.5]nonane → (1-Chloro-5-methylisoquinolin-4-yl)(2-oxa-7-azaspiro[3.5]nonan-7-yl)methanone

https://huagongshe.com/reaction/1470475

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxa-7-azaspiro[3.5]nonaneHCID 21955284—
ReactantHCID 84687221HCID 84687221—
Product(1-Chloro-5-methylisoquinolin-4-yl)(2-oxa-7-azaspiro[3.5]nonan-7-yl)methanoneHCID 86689591—

Reaction Steps

The title compound was prepared by using 1-chloro-5-methylisoquinolin-4-carboxylic acid (Intermediate-10) and 2-oxa-7-azaspiro[3.5]nonane by following the similar procedure as described for intermediate-11a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09006442B2
Source datasetuspto-grants-2015_04
ORD IDord-a16c381c4d6f44b8aa6fc36ada03b9ef
Source noteuspto-grants-2015_04