Thiomorpholine 1,1-dioxide → HCID 86689592, compound

HRID 1470476Notes

Reaction equation

HRID 1470476 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH3:12])[CH:8]=[CH:9][CH:10]=2)[C:5]([C:13]([OH:15])=O)=[CH:4][N:3]=1.[O:16]=[S:17]1(=[O:23])[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH3:12])[CH:8]=[CH:9][CH:10]=2)[C:5]([C:13]([N:20]2[CH2:21][CH2:22][S:17](=[O:23])(=[O:16])[CH2:18][CH2:19]2)=[O:15])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 6484228Thiomorpholine 1,1-dioxideHCID 84687221HCID 84687221, compound

Product 1

HCID 86689592HCID 86689592, compound

Procedure

The title compound was prepared by using 1-chloro-5-methylisoquinolin-4-carboxylic acid (Intermediate-10) and 1,1-dioxidothiomorpholine by following the similar procedure as described for intermediate-11a.

Sources & evidence

ORD record
ord-1851439316764ceaadf4ff8e211cd11b
Source dataset
uspto-grants-2015_04
Patent number
US09006442B2

Reaction notes

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