HCID 69669258, compound → HCID 69669262, compound

Participants

Reaction Steps

The compound 9 (70 mg, 0.18 mmol) was stirred in 10% TFA in dichloromethane (10 mL) at room temperature for 1 hour and extracted with ethyl acetate with aqueous NaHCO3. The organic layer was dried over Na2SO4, and the filtrate was concentrated to give intermediate D (50 mg, 96%). 1H-NMR (CD3OD) 8.02 (s, 1H), 7.59-7.78 (m, 5H), 7.00-7.07 (m, 2H), 6.80 (m, 3H), 3.09 (s, 6H) ppm; ESI-MS m/z calcd for C19H18N2O: 290.3590. found 291.1821 [M+1].

Provenance & Evidence