Sulfuric Acid → HCID 3682022, compound

HRID 1470586Notes

Reaction equation

HRID 1470586 reaction equation
ON=[CH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[N+:15]([O-:17])=[O:16])=[O:5].[OH:18]S(O)(=O)=O>>[CH3:14][O:13][C:10]1[CH:11]=[C:12]2[C:7](=[C:8]([N+:15]([O-:17])=[O:16])[CH:9]=1)[NH:6][C:4](=[O:5])[C:3]2=[O:18]

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 23255692HCID 23255692, compound

Product 1

HCID 3682022HCID 3682022, compound

Conditions

Temperature
80 °C

Procedure

2-Hydroxyimino-N-(4-methoxy-2-nitro-phenyl)-acetamide (5 g, 22 mmol) was added portion wise to a hot solution of conc. H2SO4 (20 mL, 4 vol) at 60° C. After completion of the addition, temperature was raised to 80° C. and maintained the same for one hour. After completion of the reaction, the reaction mixture was poured on to the crushed ice and the resulting precipitate separated was filtered, washed with water (2-3 times) and dried under vacuum to obtain the title compound as brick red colored solid which was used directly for the next reaction.

Workup

  1. additionAfter completion of the addition, temperature
  2. temperaturemaintained the same for one hour
  3. customAfter completion of the reaction
  4. customthe resulting precipitate separated
  5. filtrationwas filtered
  6. washwashed with water (2-3 times)
  7. customdried under vacuum

Sources & evidence

ORD record
ord-015494c8b28945968cf754eb8a1f613c
Source dataset
uspto-grants-2015_04
Patent number
US09006454B2

Reaction notes

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