反应详情

温度

85 °C

2-(hydroxyimino)-N-(2-iodophenyl)acetamide (3.2 g, 0.011 mmol) was added to conc. H2SO4 (15 mL) in small portions at 60° C. The reaction mixture was further heated at 85° C. for 5 h. After the reaction completion, the reaction mixture was cooled to room temperature and poured into crushed ice. A brown color solid product precipitated. It was then filtered and washed with chilled water several times, then dried in a vacuum oven to get 2.9 g of the required product as a red coloured solid (87%).

1. temperatureAfter the reaction completion, the reaction mixture was cooled to room temperature
2. additionpoured
3. custominto crushed ice
4. customA brown color solid product precipitated
5. filtrationIt was then filtered
6. washwashed with chilled water several times
7. customdried in a vacuum oven