HCID 178462443, compound → 4-Bromo-2-ethoxy-5-fluoropyridine

HRID 1470722Notes

Reaction equation

HRID 1470722 reaction equation

[Br:1][C:2]1[C:7]([F:8])=[CH:6][N:5]=[C:4]([OH:9])[CH:3]=1.[CH2:10](I)[CH3:11]>C(Cl)Cl.C(=O)([O-])[O-].[Ag+2]>[Br:1][C:2]1[C:7]([F:8])=[CH:6][N:5]=[C:4]([O:9][CH2:10][CH3:11])[CH:3]=1

Participants

4

Reactant 1

HCID 178462443HCID 178462443, compound

Product 1

HCID 671254624-Bromo-2-ethoxy-5-fluoropyridine

Reagents, catalysts & solvents 2

HCID 178418647HCID 178418647, compoundCatalyst

HCID 6344DichloromethaneSolvent

Procedure

Educt: 4-bromo-5-fluoro-pyridin-2-ol/ethyl iodide using silver carbonate in methylene chloride as a base

Sources & evidence

ORD record: ord-c5bbc50688e748af9bbcd5653589406e
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09006450B2

Reaction notes

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