反应详情

温度

40 °C

To a mixture of lead tetraacetate (2.15 g, 4.85 mmol) and mercuric diacetate (0.15 g, 0.47 mmol), thoroughly flushed with nitrogen, is added anhydrous chloroform (6 ml). This mixture is warmed to 40° C., and 5-chloro-2-methylphenylboronic acid (0.76 g, 4.46 mmol) is added in one portion, and the suspension is heated at this temperature for 5 hours. After cooling to room temperature the mixture is concentrated to a small volume then triturated with hexanes and filtered to yield crude 5-chloro-2-methylphenyllead triacetate (2.27 g).

1. customthoroughly flushed with nitrogen
2. additionis added anhydrous chloroform (6 ml)
3. temperaturethe suspension is heated at this temperature for 5 hours
4. temperatureAfter cooling to room temperature the mixture
5. concentrationis concentrated to a small volume
6. customthen triturated with hexanes
7. filtrationfiltered