4-Cyclohexylbenzenamine → HCID 67236824, compound

HRID 1470967Notes

Reaction equation

HRID 1470967 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][CH2:10][C:11]([C:13]2[CH:18]=[CH:17][C:16]([Br:19])=[CH:15][CH:14]=2)=O)=[CH:4][CH:3]=1.[CH:21]1([C:27]2[CH:33]=[CH:32][C:30]([NH2:31])=[CH:29][CH:28]=2)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:31]([C:30]3[CH:32]=[CH:33][C:27]([CH:21]4[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]4)=[CH:28][CH:29]=3)[C:11]([C:13]3[CH:18]=[CH:17][C:16]([Br:19])=[CH:15][CH:14]=3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 807644-CyclohexylbenzenamineHCID 2192171,4-Bis(4-bromophenyl)-1,4-butanedione

Product 1

HCID 67236824HCID 67236824, compoundYield 91%

Procedure

The product from Example 26E and 4-cyclohexylaniline (Alfa) were processed using the method described in Example 26F to provide 1.23 g (91%) of the title compound. 1H NMR (400 MHz, benzene-D6) δ 1.09 (s, 5H) 1.60 (s, 5H) 2.14 (s, 1H) 6.52 (s, 2H) 6.67 (s, 4H) 6.84 (s, 4H) 7.11 (s, 4H).

Sources & evidence

ORD record
ord-aa0de798cf9640dc82fd490defd51aa5
Source dataset
uspto-grants-2015_04
Patent number
US09006387B2

Reaction notes

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