HCID 86649129, compound → HCID 67236786, compound

HRID 1471055Notes

Reaction equation

HRID 1471055 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C@H:10]2[CH2:14][CH2:13][C@H:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-])=O)[CH:16]=3)[N:11]2[C:24]2[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][CH:25]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>CO.ClCCl>[F:33][C:30]([F:31])([F:32])[C:27]1[CH:26]=[CH:25][C:24]([N:11]2[C@@H:12]([C:15]3[CH:16]=[C:17]([CH:18]=[CH:19][CH:20]=3)[NH2:21])[CH2:13][CH2:14][C@@H:10]2[C:6]2[CH:5]=[C:4]([CH:9]=[CH:8][CH:7]=2)[NH2:1])=[CH:29][CH:28]=1

Participants

3

Reactant 1

HCID 86649129HCID 86649129, compound

Product 1

HCID 67236786HCID 67236786, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

The product from Example 205B was processed using the method described in Example 55E. The title compound was isolated by flash chromatography (silica gel, methanol/dichloromethane). MS (ESI) m/z 398 (M+H)+, 396 (M−H)+.

Sources & evidence

ORD record
ord-1268bf26e0b9495688213185ab5c2638
Source dataset
uspto-grants-2015_04
Patent number
US09006387B2

Reaction notes

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