HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Aminoethyl)-2,6-dimethoxyphenol → HCID 58603449, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Aminoethyl)-2,6-dimethoxyphenol | HCID 533955 | — |
| Reactant | (3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-propyl)-carbamic acid tert-butyl ester | HCID 86603242 | — |
| Product | HCID 58603449 | HCID 58603449 | — |
Reaction Steps
Intermediate 4 was coupled with 4-(2-Amino-ethyl)-2,6-dimethoxy-phenol following procedure F and the resulting product deprotected following procedure G. LC-MS showed the product had the expected M+H+ of 516. 1H NMR (Varian 300 MHz, CD3OD, shifts relative to the solvent peak at 3.3 ppm) δ 8.26 (d, 1H) 8.21 (s, 1H) 8.12 (d, 1H) 7.68 (d, 1H) 7.58 (d, 1H) 7.33 (d, 1H) 6.53 (s, 2H) 4.50 (s, 2H) 3.76 (s, 6H) 3.37 (m, 2H) 2.97 (s, 3H) 2.9 (m, 2H) 2.81 (m, 2H) 1.70 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732444B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-c9fd6ec5fee94a539079e10a1a147fb8 |
| Source note | uspto-grants-2010_06 |