HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178446054, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | L-Leucine | HCID 6106 | — |
| Reactant | Trehalose | HCID 7427 | — |
| Reactant | HCID 178480554 | HCID 178480554 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178446054 | HCID 178446054 | — |
Reaction Steps
Tiotropium bromide (1.4 g), trehalose dehydrate (0.3 g) and L-leucine (0.3 g) were dissolved into methanol (60 ml). The solution was shaken. Water (60 ml) was added and shaken until dissolution occurred. The resultant solution was spray dried according to the parameters outlined below.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09011923B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-326851c600ac40fa98125d7077247570 |
| Source note | uspto-grants-2015_04 |