HCID 68771630, compound → HCID 68770987, compound

Participants

Reaction Steps

A solution of (E)-1-(rel-(6S,7R)-7-methylspiro[4.5]dec-8-en-6-yl)but-2-en-1-one (2.0 g, 9.16 mmol) in ethanol (30 ml) was treated with 10% Pd/C (0.4 g) and hydrogenated (20 bar) for 1.5 h. The resulting mixture was filtered and concentrated. FC (SiO2, hexane/MTBE 50:1) of the crude product (1.9 g) gave 1-(rel-(6S,7R)-7-methylspiro[4.5]decan-6-yl)butan-1-one (0.75 g, 37%). Boiling point: 95° C. (0.08 mbar).

Provenance & Evidence