HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Benzyloxy)-5-(methoxymethoxy)pyridine → HCID 178498305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Benzyloxy)-5-(methoxymethoxy)pyridine | HCID 67217684 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178498305 | HCID 178498305 | 0.1% |
Reaction Steps
To 2-(benzyloxy)-5-(methoxymethoxy)pyridine (1.8 g, 8.71 mol) in EtOH was added Pd/C (1.0 g). The mixture was charged with H2 (15 psi), stirred at rt for 45 min, filtered, and concentrated to give 5-(methoxymethoxy)pyridin-2-ol (1.35 g, quantitative yield) as a pale yellow solid. LRMS (M+H+) m/z 156.1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012450B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-cc7ab61bd8ca4d61808166c7062ba31d |
| Source note | uspto-grants-2015_04 |