HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Cyano-3-fluorophenyl)boronic acid → HCID 71736415, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Cyano-3-fluorophenyl)boronic acid | HCID 2783130 | — |
| Reactant | 4-(5-Chlorofuro[2,3-c]pyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester | HCID 86674889 | — |
| Product | HCID 71736415 | HCID 71736415 | — |
Reaction Steps
The title compound is prepared from 4-(5-chloro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester and 4-cyano-3-fluoro-phenylboronic acid following a procedure analogous to that described for Example 1; the reaction is conducted at 150° C. LC (method 4): tR=1.84 min; Mass spectrum (ESI+): m/z=422 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012456B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-87aaec023fd04df9ad95bd53a52aa6e0 |
| Source note | uspto-grants-2015_04 |