HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylcyclopropyl 4-nitrophenyl carbonate → 4-[5-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid 1-methyl-cyclopropyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylcyclopropyl 4-nitrophenyl carbonate | HCID 57930115 | — |
| Reactant | 5-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-furo[2,3-c]pyridine | HCID 86694580 | — |
| Product | 4-[5-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid 1-methyl-cyclopropyl ester | HCID 86694581 | — |
Reaction Steps
The title compound is prepared from 5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-furo[2,3-c]pyridine and 1-methyl-cyclopropyl 4-nitrophenyl carbonate following a procedure analogous to that described for Example 20. Mass spectrum (ESI+): m/z=460 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012456B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-b157f99386f7497f9db346bd7248d391 |
| Source note | uspto-grants-2015_04 |