4-(Methanesulfonyl)phenylboronic acid → 4-[5-(4-Methanesulfonyl-phenyl)-furo[2,3-c]pyridin-2-yl]-4-methyl-piperidine-1-carboxylic acid tert-butyl ester

Participants

Reaction Steps

The title compound is prepared from 4-(5-chloro-furo[2,3-c]pyridin-2-yl)-4-methyl-piperidine-1-carboxylic acid tert-butyl ester and 4-methanesulfonyl-phenylboronic acid following a procedure analogous to that described for Example 1; the reaction is conducted at 150° C. LC (method 4): tR=1.71 min; Mass spectrum (ESI+): m/z=471 [M+H]+.

Provenance & Evidence