HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Anilino-2,5-dichloropyrimidine → 5-chloro-N2-[6-(dimethylphosphoryl)-2-methoxypyridin-3-yl]-N4-phenylpyrimidine-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Anilino-2,5-dichloropyrimidine | HCID 18768047 | — |
| Reactant | (5-Amino-6-methoxypyridin-2-yl)dimethylphosphine oxide | HCID 67052694 | — |
| Product | 5-chloro-N2-[6-(dimethylphosphoryl)-2-methoxypyridin-3-yl]-N4-phenylpyrimidine-2,4-diamine | HCID 68156907 | — |
Reaction Steps
This compound can be prepared as in Example 32 by reacting 2,5-dichloro-N-phenylpyrimidin-4-amine with 6-(Dimethylphosphoryl)-2-methoxypyridin-3-ylamine (prepared in Example 32)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012462B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-a7b7f7b568f242798793db6b36a07a96 |
| Source note | uspto-grants-2015_04 |