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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1471998Generated: October 28, 2026

2,6-Dimethoxypyridin-3-amine → 5-chloro-N2-[6-(dimethylphosphoryl)-2-methoxypyridin-3-yl]-N4-[4-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine

https://huagongshe.com/reaction/1471998

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethoxypyridin-3-amineHCID 593005—
ReactantHCID 86668790HCID 86668790—
Product5-chloro-N2-[6-(dimethylphosphoryl)-2-methoxypyridin-3-yl]-N4-[4-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamineHCID 86668797—

Reaction Steps

This compound can be prepared as in Example 32 by reacting 2,5-dichloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amine with 2,6-Dimethoxypyridin-3-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09012462B2
Source datasetuspto-grants-2015_04
ORD IDord-93f28947523b4f00adb60e7a3743ba6d
Source noteuspto-grants-2015_04