2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → 2-methyl-N-[3-[1-[2-methyl-3-(2,4,5-trifluorophenoxy)propyl]piperidin-4-yl]phenyl]propanamide
Reaction equation
[CH3:16][CH:17]([C:18](=[O:19])[NH:20][c:21]1[cH:22][c:23]([CH:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[cH:24][cH:25][cH:26]1)[CH3:33].[Cl:1][CH2:2][CH:3]([CH2:4][O:5][c:6]1[c:7]([F:14])[cH:8][c:9]([F:13])[c:10]([F:12])[cH:11]1)[CH3:15]>>[CH2:2]([CH:3]([CH2:4][O:5][c:6]1[c:7]([F:14])[cH:8][c:9]([F:13])[c:10]([F:12])[cH:11]1)[CH3:15])[N:30]1[CH2:29][CH2:28][CH:27]([c:23]2[cH:22][c:21]([NH:20][C:18]([CH:17]([CH3:16])[CH3:33])=[O:19])[cH:26][cH:25][cH:24]2)[CH2:32][CH2:31]1Participants
3
Sources & evidence
- ORD record
- ord-001b6f896a8545ff99dc5bc7544fd86b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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