Benzylamine → HCID 68165239, compound

HRID 1472020Notes

Reaction equation

[Cl:1][C:2]1[C:3]([NH:26][C:27]2[CH:32]=[CH:31][C:30]([P:33]([CH3:36])([CH3:35])=[O:34])=[CH:29][C:28]=2[S:37]([CH:40]([CH3:42])[CH3:41])(=[O:39])=[O:38])=[N:4][C:5]([NH:8]C2OC(N3CCN(C4C=CC=CN=4)CC3)=NN=2)=[N:6][CH:7]=1.[CH2:43](N)[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1>>[CH2:43]([NH:8][C:5]1[N:4]=[C:3]([NH:26][C:27]2[CH:32]=[CH:31][C:30]([P:33]([CH3:36])([CH3:35])=[O:34])=[CH:29][C:28]=2[S:37]([CH:40]([CH3:41])[CH3:42])(=[O:39])=[O:38])[C:2]([Cl:1])=[CH:7][N:6]=1)[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1

Participants

Reactant 2

HCID 7504Benzylamine

HCID 68157416HCID 68157416, compound

Product 1

HCID 68165239HCID 68165239, compound

Procedure

This compound can be prepared as in Example 32 by reacting 2,5-dichloro-N-[4-(dimethylphosphoryl)-2-(propan-2-ylsulfonyl)phenyl]pyrimidin-4-amine (as described in Example 53) with benzylamine.

Workup

customThis compound can be prepared as in Example 32

Sources & evidence

ORD record: ord-acaa6f69f61c4b1cb93e577f6de4559f
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09012462B2

Reaction notes

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