HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → HCID 68156944, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 6-chloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amine | HCID 86668807 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68156944 | HCID 68156944 | — |
Reaction Steps
To a solution of 6-chloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amine (prepared as in Example 59: 0.12 mmol) in 2 mL of ethanol is added 50 μL of triethylamine and 1-Phenylpiperazine (19 mg, 0.12 mmol). The mixture is microwaved at 120 degrees until formation of the desired compound. The reaction mixture can then be filtered through a syringe filter and purified by prep-HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09012462B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-0db5145a6ff14c7f980162121c9bee8b |
| Source note | uspto-grants-2015_04 |