Tricyclo(3.3.1.13,7)dec-1-ylmethylamine → HCID 68156897, compound
Reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([P:15]([CH3:18])([CH3:17])=[O:16])=[CH:11][CH:10]=2)[CH:3]=1.[C:19]12([CH2:29][NH2:30])[CH2:28][CH:23]3[CH2:24][CH:25]([CH2:27][CH:21]([CH2:22]3)[CH2:20]1)[CH2:26]2>>[CH3:17][P:15]([C:12]1[CH:13]=[CH:14][C:9]([NH:8][C:4]2[CH:3]=[C:2]([NH:30][CH2:29][C:19]34[CH2:28][CH:23]5[CH2:22][CH:21]([CH2:27][CH:25]([CH2:24]5)[CH2:26]3)[CH2:20]4)[N:7]=[CH:6][N:5]=2)=[CH:10][CH:11]=1)([CH3:18])=[O:16]Participants
3
Procedure
The compound is prepared as in Example 59 by reacting 6-chloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amine with 1-adamantanemethylamine.
Workup
- customThe compound is prepared as in Example 59
Sources & evidence
- ORD record
- ord-f4ed1f7920b247bd9d1ab0cf7901d490
- Source dataset
- uspto-grants-2015_04
- Patent number
- US09012462B2
Reaction notes
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