3,5-Dimethylaniline → HCID 68156809, compound
Reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([P:15]([CH3:18])([CH3:17])=[O:16])=[CH:11][CH:10]=2)[CH:3]=1.[CH3:19][C:20]1[CH:21]=[C:22]([CH:24]=[C:25]([CH3:27])[CH:26]=1)[NH2:23]>>[CH3:19][C:20]1[CH:21]=[C:22]([NH:23][C:2]2[CH:3]=[C:4]([NH:8][C:9]3[CH:14]=[CH:13][C:12]([P:15]([CH3:18])([CH3:17])=[O:16])=[CH:11][CH:10]=3)[N:5]=[CH:6][N:7]=2)[CH:24]=[C:25]([CH3:27])[CH:26]=1Participants
3
Procedure
The compound is prepared as in Example 59 by reacting 6-chloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amine with 3,5-dimethylaniline.
Workup
- customThe compound is prepared as in Example 59
Sources & evidence
- ORD record
- ord-976ed80147a942eb95360aa21355e749
- Source dataset
- uspto-grants-2015_04
- Patent number
- US09012462B2
Reaction notes
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