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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1472205Generated: October 31, 2026

Methanol → Methyl 2,4-Difluorobenzoate

https://huagongshe.com/reaction/1472205

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant2,4-Difluorobenzoyl chlorideHCID 588081—
ProductMethyl 2,4-DifluorobenzoateHCID 2782897—

Reaction Steps

To 100 mL of methanol, 2,4-difluoro-benzoyl chloride (10 mL, 79.3 mmol) was added and the mixture stirred at room temperature for 2 hours. The solvent was then evaporated affording the title compound as pale yellow oil (quantitative).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09012487B2
Source datasetuspto-grants-2015_04
ORD IDord-7631d164f3064544879f3f2aa42d567a
Source noteuspto-grants-2015_04