Ammonia → 5-[6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3H-imidazo[4,5-c]pyridin-3-yl]-3-{1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14](-[c:17]1[cH:18][c:19]([O:26][CH:27]([CH3:28])[c:29]3[c:30]([C:35]([F:36])([F:37])[F:38])[cH:31][cH:32][cH:33][cH:34]3)[c:20]([C:22]([O:24][CH3:23])=[O:25])[s:21]1)[cH:15][n:16]2)([CH3:39])[CH3:40].[CH3:42][OH:43].[NH3:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14](-[c:17]1[cH:18][c:19]([O:26][CH:27]([CH3:28])[c:29]3[c:30]([C:35]([F:36])([F:37])[F:38])[cH:31][cH:32][cH:33][cH:34]3)[c:20]([C:22](=[O:24])[NH2:41])[s:21]1)[cH:15][n:16]2)([CH3:39])[CH3:40]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-1d958016184143c19d5fdc186d0a72b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…