HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1472657Generated: October 31, 2026
Tert-butyl 2-(4-(6-hydroxyquinolin-2-yl)benzoyl)hydrazinecarboxylate → 4-(6-Hydroxyquinolin-2-yl)benzohydrazide
https://huagongshe.com/reaction/1472657
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tert-butyl 2-(4-(6-hydroxyquinolin-2-yl)benzoyl)hydrazinecarboxylate | HCID 66980037 | — |
| Solvent | Hydrochloride methanol | HCID 21893726 | — |
| Product | 4-(6-Hydroxyquinolin-2-yl)benzohydrazide | HCID 66980074 | 68% |
Reaction Steps
A mixture of tert-butyl 2-(4-(6-hydroxyquinolin-2-yl)benzoyl)hydrazinecarboxylate (240 mg, 0.633 mmol) and HCl/MeOH (20 mL, 4M) was stirred at 25° C. overnight. The resulting mixture was concentrated under reduced pressure to dryness to give the product (120 mg, yield 68%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09012646B2 |
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| Source dataset | uspto-grants-2015_04 |
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| ORD ID | ord-faf76ad1928c4e7a931a356d5c4c1218 |
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| Source note | uspto-grants-2015_04 |
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