HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1472701Generated: October 30, 2026
HCID 53212388, compound → HCID 67975090, compound
https://huagongshe.com/reaction/1472701
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 53212388 | HCID 53212388 | — |
| Reactant | 4-(4,4,5,5-Tetramethyl-(1,3,2)dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylic acid ethyl ester | HCID 59278796 | — |
| Product | HCID 67975090 | HCID 67975090 | 55% |
Reaction Steps
Followed the coupling procedure similar to that described in Compound VIII-2 (Example 65), where the starting materials were ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate and 2-chloro-6-methoxy-3-(trifluoromethyl)quinoxaline (Intermediate 11) and where the reaction here was stirred under N2 atmosphere at 100° C. for 3 hours. Ethyl 4-(6-methoxy-3-(trifluoromethyl)quinoxalin-2-yl)cyclohex-3-enecarboxylate was isolated (800 mg, yield 55%) as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09012646B2 |
|---|
| Source dataset | uspto-grants-2015_04 |
|---|
| ORD ID | ord-9a8a47459ed1436d9eb327e14447e66f |
|---|
| Source note | uspto-grants-2015_04 |
|---|
