1-Nonanol, 9-bromo- → 9-Bromononanoic Acid

Participants

Reaction Steps

Pyridinium chlorochromate (38.7 g, 180 mmol) and silica 60A (39 g, particle size 35-70 micron) suspended in dichloromethane (250 mL) were stirred at RT for 45 minutes. 9-Bromononanol (26.7 g, 120 mmol) was added, in one portion, and the suspension was stirred at RT for 18 hours. The reaction mixture was filtered through a column of celite and the resultant filtrate concentrated under vacuum affording the title compound (28.0 g, >100%).

Provenance & Evidence