Hydrochloric Acid → HCID 15434420, compound

Participants

Reaction Steps

10 g (R)-4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-benzoic acid hydrochloride of formula (G) was added in 10 ml toluene followed by slow addition of 3.2 g Vitride in above solution at 0° C. to 5° C. within 15 minutes. Further 20% HCl solution was added and toluene layer washed with water. Distillation of toluene layer afforded the title compound as (R)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol of formula (H).

Provenance & Evidence