(1-Bromoethyl)benzene → HCID 71538478, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 2 from methyl 2-(tert-butoxy)-2-(4-(4-chlorophenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-5-yl)acetate and (1-bromoethyl)benzene and was isolated as a white solid (4.5 mg, 37% yield). 1H NMR (400 MHz, CHLOROFORM-d) ppm 7.65-7.58 (m, 1H), 7.50-7.44 (m, 2H), 7.44-7.38 (m, 1H), 7.38-7.28 (m, 4H), 7.18-7.12 (m, 1H), 7.12-7.04 (m, 1H), 6.02-5.96 (m, 1H), 5.34 (s, 1H), 4.58-4.22 (m, 1H), 3.69 (s, 3H), 1.93-1.82 (m, 3H), 1.02-1.04 (m, 9H); LCMS (m/z) ES+=493 (M+1).

Provenance & Evidence