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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1474131Generated: November 3, 2026

Nitrate(1-), oxo- → HCID 66644843, compound

https://huagongshe.com/reaction/1474131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitrate(1-), oxo-HCID 3001380—
Reactant3-Amino-2-hydroxy-4-phenylbutanamideHCID 13882355—
ReactantHCID 66644628HCID 66644628—
ReactantHCID 178514248HCID 178514248—
ProductHCID 66644843HCID 66644843—

Reaction Steps

Coupling of (R)-5-Oxo-1-(2-trifluoromethyl-benzyl)-pyrrolidine-2-carboxylic acid with 3-amino-2-hydroxy-4-phenylbutanamide and oxidation of the resulting hydroxyamide intermediate to the corresponding ketoamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09018206B2
Source datasetuspto-grants-2015_04
ORD IDord-fe09f3709e8b4ec8a4ba862184937400
Source noteuspto-grants-2015_04