反应详情

A mixture of 5-bromo-4,7-dimethyl-2-benzofuran-1(3H)-one (0.7 g, 2.9 mmol), potassium vinyltrifluoroborate (0.544 g, 4 mmol) and Pd(dppf)2Cl2 (0.07 g) in 20 mL of EtOH and 20 mL of TEA was refluxed under N2 for 4 hours. The mixture was concentrated and the residue was purified by column chromatography to afford 4,7-Dimethyl-5-vinyl-2-benzofuran-1(3H)-one.

1. temperaturewas refluxed under N2 for 4 hours
2. concentrationThe mixture was concentrated
3. customthe residue was purified by column chromatography