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HRID1474415

反应详情

EQUATION

反应方程式

HRID 1474415 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc2c(cc1C1CO1)COC2=O
HCID59568662

未命名化合物

结构：Cc1c([C@@H](O)CN2CCNCC2)ccc2c1COC2=O
HCID59568728

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc2c(cc1C(O)CN1CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC1)COC2=O
HCID59568659

未命名化合物

PROCEDURE

实验过程

5-[(1R)-1-hydroxy-2-{4-[2-hydroxy-2-(6-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin-1-yl}ethyl]-4-methyl-2-benzofuran-1(3H)-one was prepared in a similar fashion to that described for the synthesis of EXAMPLE 58 starting from 5-[(1R)-1-hydroxy-2-(piperazin-1-yl)ethyl]-4-methyl-2-benzofuran-1(3H)-one and isomer B of 6-methyl-5-oxiran-2-yl-2-benzofuran-1(3H)-one (65B).