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HRID14745

反应详情

EQUATION

反应方程式

HRID 14745 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCC(=O)C1
HCID471360

N-Boc-3-pyrrolidinone

C9H15NO3

结构：Nc1cccc(-c2ccnc(Cl)n2)c1
HCID59341023

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(Nc2cccc(-c3ccnc(Cl)n3)c2)C1
HCID86603246

未命名化合物

收率 70%

PROCEDURE

实验过程

Intermediate 6 was coupled with 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester following procedure J. The product was purified on silica gel using 1:1 ethyl acetate:hexanes as eluent. Yield: 70%. LC-MS showed the product had the expected M+H+ of 375.

WORKUP

后处理

  1. customThe product was purified on silica gel using 1:1 ethyl acetate