HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl octanoate → 1-(Octanoyloxy)ethyl-5-amino-4-oxopentanoate Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl octanoate | HCID 229780 | — |
| Reactant | 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid | HCID 17989820 | — |
| Product | 1-(Octanoyloxy)ethyl-5-amino-4-oxopentanoate Hydrochloride | HCID 86709204 | — |
Reaction Steps
The compound was prepared as described in Procedures A and B above from 2-chloroethyloctanoate and 5-(tert-butoxycarbonylamino)-4-oxopentanoic acid. 1H-NMR (300 MHz, CDCl3) ppm δ 0.87 (t, J=7.20 Hz, 3H, CH2Me), 1.27 (m, 8H, (CH2)4CH2CH2CO2), 1.45 (d, J=5.40 Hz, 3H, OCH(CH3)O), 1.58 (sext, J=7.32 Hz, 2H, CH2CH2CH2CO2), 2.28 (t, J=7.30 Hz, 2H, CH2CH2CH2CO2), 2.66 (“t”, 2H, COCH2CH2CO2), 2.94 (“t”, 2H, COCH2CH2CO2), 4.28 (s, 2H, CH2NH2), 6.83 (q, J=5.60 Hz, 1H, OCHO).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018257B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-52f95c4b120943c3beaeba9623ad6202 |
| Source note | uspto-grants-2015_04 |