Acetic Acid → HCID 89442952, compound

Participants

Reaction Steps

To a solution of (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-(4-(2-((tert-butyldimethylsilyl)oxy)ethoxy)benzyl)-4-chlorophenyl)tetrahydro-2H-pyran-3,4,5-triyltriacetate (2.59 g, 3.66 mmol) in THF:Water (1:1, 36 mL) was added acetic acid (54 mL) at 0° C. The reaction mixture was stirred at r.t. for 24 h. After completion of reaction, as confirmed by TLC, the reaction mixture was evaporated in vacuo and the residue obtained was purified by column chromatography (silica gel, 4:6 Ethyl acetate:Pet. Ether) to afford title compound (1.8 g, 82%).

Provenance & Evidence