Hydrogen Bromide → HCID 86729310, compound

Participants

Reaction Steps

To (3S,4R,5S,6S)-6-(3-(4-acetoxybenzyl)-4-chlorophenyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (2.03 g, 4.03 mmol) a 33% solution of HBr in AcOH (6 mL) was added at r.t. and stirred for 0.1 h. The reaction mixture was diluted with DCM (20 mL) and stirred for 30 min. Water was added to the resulting mixture and stirred for another 1 h. It was diluted with DCM (50 mL), washed with water (50 mL), saturated NaHCO3 solution (50 mL) and brine (50 mL). The organic layer was dried over Na2SO4 and the volatiles were evaporated in vacuo to afford the title compound (2.02 g, 90%)

Provenance & Evidence