2-(4-(benzyloxy)-2-methylphenyl)-N,N-dimethylacetamide → 2-(4-hydroxy-2-methylphenyl)-N,N-dimethylacetamide

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Reaction Steps

2-[4-(benzyloxy)-2-methylphenyl]-N,N-dimethylacetamide (680 mg, 2.40 mmol) was dissolved in ethanol (4 ml) and palladium hydroxide on carbon (20%) (169 mg, 0.240 mmol) added. The mixture was stirred under an atmosphere of hydrogen gas at RT overnight. The mixture was filtered and the filtrate concentrated under reduced pressure to afford the title compound. LC/MS (m/z): 194 (M+H)+.

Provenance & Evidence