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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 147495Generated: October 29, 2026

Dimethyl Sulfoxide → 1-(2-chlorophenyl)-2-oxo-7-(trifluoromethyl)-2,3-dihydro-1H-benzimidazole-5-carbonitrile

https://huagongshe.com/reaction/147495

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantWaterHCID 962—
ReactantTert-Butyl nitriteHCID 10906—
Reactant5-Amino-1-(2-chlorophenyl)-7-(trifluoromethyl)-1,3-dihydro-2H-benzimidazole-2-oneHCID 22327361—
ReactantHCID 178418546HCID 178418546—
Product1-(2-chlorophenyl)-2-oxo-7-(trifluoromethyl)-2,3-dihydro-1H-benzimidazole-5-carbonitrileHCID 22327397—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-4ce5f779e887489f90e90adcbff671aa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)