HuagongsheHuagongshe Chemistry Print Report · For research reference only
Manidipine → Manidipine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Manidipine | HCID 4008 | — |
| Reactant | Isopropanol hydrochloride | HCID 21912024 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Manidipine dihydrochloride | HCID 150762 | — |
Reaction Steps
Manidipine base was dissolved in acetone (15 ml). The pH of the solution was adjusted to 1-1.5 with IPA-HCl solution with constant stifling to get manidipine Dihydrochloride. The reaction mass was filtered and dried for 2 hours (yield: 3 gm).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09018376B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-dc71e9cd1adf44b5ab0ed679eaacd20c |
| Source note | uspto-grants-2015_04 |