Methyl iodide → HCID 86723979, compound

HRID 1475367Notes

Reaction equation

HRID 1475367 reaction equation
[CH2:1]([N:5]1[C:10](=[O:11])[CH:9]=[C:8]2[C:12]([CH3:16])([CH3:15])[CH2:13][NH:14][C:7]2=[CH:6]1)C(C)C.IC>>[CH3:15][C:12]1([CH3:16])[C:8]2[C:7](=[CH:6][N:5]([CH3:1])[C:10](=[O:11])[CH:9]=2)[NH:14][CH2:13]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 70981630HCID 70981630, compound

Product 1

HCID 86723979HCID 86723979, compound

Procedure

Prepared in an analogous method to 6-isobutyl-3,3-dimethyl-1,2,3,6-tetrahydro-pyrrolo[2,3-c]pyridin-5-one using iodomethane instead of 3-bromo-2-methylpropene and omitting the hydrogenation step (see Preparations 128 and 130).

Sources & evidence

ORD record
ord-02b13b7325384158bfe87c41f6ce7cbe
Source dataset
uspto-grants-2015_04
Patent number
US09018214B2

Reaction notes

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